You will skim the full text of the included articles to extract data and compile it into a table format, which will help summarize the studies and facilitate comparison. At least two reviewers should extract data from each study. Here are the steps you will follow:
Create evidence tables, which provide detailed information for each study. Additionally, summary tables offer an overview of your review's findings. You can use these tables to describe study characteristics and/or results. They will help you determine which studies may be eligible for quantitative synthesis.
Page M J, Moher D, Bossuyt P M, Boutron I, Hoffmann T C, Mulrow C D et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews BMJ 2021; 372 :n160 doi:10.1136/bmj.n160
Title
Authors
Year of publication
Journal name
Country of study
Type of study (e.g., RCT, cohort, qualitative, case study)
Duration of study
Sample size and number of study arms/groups
Method of randomization or blinding (for RCTs)
Inclusion and exclusion criteria
Number of participants enrolled and analyzed
Demographics: age, gender, ethnicity, etc.
Clinical characteristics or baseline data
Description of the intervention (e.g., drug, therapy, program)
Dosage, frequency, duration
Comparator or control group details (placebo, standard care, etc.)
Primary and secondary outcomes measured
Outcome definitions and measurement tools
Timing of outcome assessments
Results (effect sizes, confidence intervals, p-values)
Numerical data for outcomes (means, proportions, risk ratios, etc.)
Measures of variance (standard deviations, CIs)
Adverse events or unintended effects
Subgroup or sensitivity analyses
Judgments based on tools like Cochrane RoB, CASP, JBI
Notes on methodological strengths or weaknesses
Funding sources or conflicts of interest
Key quotes or themes (for qualitative studies)
Author conclusions
Comments or caveats from reviewers
To evaluate the quality of evidence for each outcome, consider using GRADE for RCTs. It classifies the evidence in four levels (very low to high) and offers 2 grades of recommendations: "strong" and "weak."
Pulling structured info: Study design, sample size, intervention, population
Highlighting outcomes: Extracting or identifying primary and secondary outcomes
Pre-filling forms: Some tools can auto-populate data extraction forms with text from PDFs
Assisting synthesis: Tagging similar findings or outcomes across studies
These tools can miss nuanced details or misinterpret context, especially with complex or poorly reported studies
Always verify extracted data manually—think of AI as a first pass, not the final word
Most tools work best with clinical trials, less so with qualitative or mixed-methods studies
Tool |
Best For |
Key Features |
Limitations |
Cost |
Elicit.org |
Early-stage reviews; scoping reviews |
Extracts sample size, outcomes, intervention, PICO |
Basic fields only; no results or appraisal |
Free |
RobotReviewer |
RCT-based systematic reviews |
Auto-risk of bias, PICO elements from PDFs |
Limited to RCTs; needs verification |
Free |
Synthesis.ai |
Comprehensive systematic reviews |
AI-assisted extraction & synthesis (in development) |
Still evolving; limited access |
Varies |
DistillerSR |
Institutional, large-scale reviews |
Custom extraction forms, audit trail, automation |
Expensive; best for trained users |
$$$ |
EPPI-Reviewer |
Advanced academic reviews |
Coding, AI-assisted tagging, handles qualitative too |
Older interface; learning curve |
$$ |
ASReview |
Screening + simple tagging |
Active learning for inclusion + metadata tagging |
Not built for full data extraction |
Free |
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